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string= abc,123,def,456                 ; etcetera
MyFn(string)

MyFn(string){
   StringSplit,split,string, `,
   Loop, % (split0/2){
      str:= "split" . (A_Index * 2 - 1) ; step 1
      str:= %str%                       ; step 2
      int:= "split" . (A_Index * 2)     ; step 3
      int:= %int%                       ; step 4
      MsgBox,, LOOP %A_Index%, String = `"%str%`"`nInteger = `"%int%`", 5
   }
   Return
}

string= abc,123,def,456
Loop,Parse,String,`,,%A_space%
   If Mod(A_Index,2) || (%var%:=A_LoopField)
      var:=A_LoopField
ListVars
MsgBox

string= abc,123,def,456                 ; etcetera
While pos := RegexMatch( string, "(?<" ( A := A_Index * 2 - 1 ) ">[^,]*),(?<" ( B := A_Index * 2 ) ">[^,]*),?", split, A_Index = 1 ? 1 : pos + StrLen( split ) )
   MsgBox,, LOOP %A_Index%, % "String = """ split%A% """`nInteger = """ split%b% """", 5