http://www.techcult.com/high-tech-pranks/
25. Hotkey Hell
Our final prank may be the most tortuous of all. A little program called AutoHotKey — quite the handy utility for legitimate purposes — lets you assign all sorts of macros to key combinations of your choosing. You don’t even have to install anything on anyone else’s computer, as you create the scripts on your own system and can then convert them to executable files that you simply run on another machine. With some very basic scripting, you can cause any string of text to be automatically replaced with something else, regardless of what program the person is in. You can also remap basic hotkeys like Ctrl-P to do anything you want — like open Outlook and send a message to you letting you know how awesome you are. Spend some time with this one and you’ll find enough pranks to keep your hijinks on high output.